Melanotan II (MT-II) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It acts as a non-selective agonist at melanocortin receptors MC1R through MC5R, with particular potency at MC3R and MC4R, making it a widely used research tool for melanocortin system pharmacology.
Research Applications:
- Melanocortin receptor binding and signaling studies
- Pigmentation and melanogenesis research (MC1R)
- Energy balance and food intake regulation (MC3R/MC4R)
- Sexual behavior and erectile physiology research in animal models
Key Properties:
Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
Molecular Formula: C₅₀H₆₉N₁₅O₉
Molecular Weight: 1,024.2 Da
CAS: 121062-08-6
Product Specifications:
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: −20 °C, protected from light
For research use only. Not for human consumption. Not for veterinary use. No medical or therapeutic claims are made. These statements have not been evaluated by the FDA.

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