GHK-Cu (glycyl-L-histidyl-L-lysine copper(II)) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine that declines significantly with age. It has a strong affinity for copper(II) ions and activates a broad array of genes involved in tissue remodeling, collagen synthesis, angiogenesis, and antioxidant defense.
Research Applications:
- Wound healing, angiogenesis, and collagen synthesis studies
- MMP and TIMP regulation in extracellular matrix remodeling
- Skin biology and dermal fibroblast research
- Anti-inflammatory and antioxidant gene expression studies
- Neuroplasticity and nerve regeneration research
Key Properties:
Sequence: Gly-His-Lys (copper complex)
Molecular Formula: C₁₄H₂₂CuN₆O₄
Molecular Weight: 403.9 Da
CAS: 89030-95-5
Product Specifications:
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: −20 °C, protected from light
For research use only. Not for human consumption. Not for veterinary use. No medical or therapeutic claims are made. These statements have not been evaluated by the FDA.

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