Sermorelin

Sermorelin (GRF 1-29 NH₂) is a synthetic 29-amino acid amide corresponding to the biologically active N-terminal fragment of human growth hormone-releasing hormone (GHRH). It is the shortest GHRH fragment retaining full in vivo GH-releasing potency, binding selectively to the GHRH receptor (GHRHR) on pituitary somatotroph cells.

Research Applications:

• GHRHR binding kinetics and receptor pharmacology
• Pulsatile GH secretion and somatotroph physiology
• Pituitary function assessment in animal models
• IGF-1 axis and growth regulation research
• Sleep architecture studies (GH-SWS relationship)

Key Properties:
Sequence: GHRH(1-29)-NH₂
Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular Weight: 3,357.9 Da
CAS: 86168-78-7

Product Specifications:
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: −20 °C, protected from light

For research use only. Not for human consumption. Not for veterinary use. No medical or therapeutic claims are made. These statements have not been evaluated by the FDA.