NAD+

Nicotinamide Adenine Dinucleotide (NAD⁺) is the oxidized form of the essential coenzyme involved in hundreds of metabolic reactions as an electron carrier. Beyond its role in glycolysis and the TCA cycle, NAD⁺ serves as the obligate substrate for sirtuins (SIRT1–7), PARPs, and CD38/CD157 ectoenzymes — making it central to epigenetic regulation, DNA repair, and cellular stress responses.

Research Applications:

• Sirtuin (SIRT1–7) activation and deacylation studies
• PARP-mediated DNA repair and genotoxic stress research
• Mitochondrial bioenergetics and OXPHOS studies
• Aging and longevity pathway research (NAD⁺ decline models)
• Circadian clock regulation via SIRT1/CLOCK-BMAL1

Key Properties:
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.4 Da
CAS: 53-84-9

Product Specifications:
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: −20 °C, protected from light

For research use only. Not for human consumption. Not for veterinary use. No medical or therapeutic claims are made. These statements have not been evaluated by the FDA.