Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic heptapeptide derived from the immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro extension for CNS stability. It modulates GABAergic, serotonergic, and dopaminergic neurotransmission and has been studied as an anxiolytic and cognition-enhancing agent in animal models.
Research Applications:
- Anxiolytic mechanism studies (GABAergic modulation)
- BDNF/trkB signaling and neuroplasticity research
- Immune cell function and cytokine balance studies
- Memory consolidation and cognitive performance research
- HPA axis and stress response modulation
Key Properties:
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular Formula: C₃₃H₅₇N₉O₁₁
Molecular Weight: 751.9 Da
CAS: 129954-34-3
Product Specifications:
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: −20 °C, protected from light
For research use only. Not for human consumption. Not for veterinary use. No medical or therapeutic claims are made. These statements have not been evaluated by the FDA.

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