IGF-1 LR3 is an 83-amino acid analog of human Insulin-like Growth Factor-1 engineered with a 13-residue N-terminal extension and an Arg³ substitution. These modifications reduce binding to IGF-binding proteins, extending its serum half-life to approximately 20–30 hours versus the ~12 minutes of native IGF-1.
Research Applications:
- Cellular proliferation and differentiation studies
- Muscle satellite cell and myoblast research
- Metabolic signaling pathway investigations (PI3K/Akt/mTOR)
- IGF-1 receptor binding and downstream signaling studies
Key Properties:
Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
Molecular Weight: ~9,117 Da
CAS: 946870-92-4
Product Specifications:
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: −20 °C, protected from light
For research use only. Not for human consumption. Not for veterinary use. No medical or therapeutic claims are made. These statements have not been evaluated by the FDA.

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