GLP 3 RT (Retatrutide) is a long-acting peptide agonist that simultaneously activates three receptors: glucose-dependent insulinotropic polypeptide receptor (GIPR), glucagon-like peptide-1 receptor (GLP-1R), and glucagon receptor (GCGR). This triple-agonist mechanism positions it among the most potent metabolic research tools currently available.
Research Applications:
- Obesity and adipose tissue biology research
- Glucose homeostasis and insulin secretion studies
- Energy expenditure and thermogenesis investigation
- Comparative receptor pharmacology (GIP vs GLP-1 vs GCG axes)
- Non-alcoholic fatty liver disease (NAFLD/NASH) preclinical models
Key Properties:
Receptor Targets: GIPR, GLP-1R, GCGR
Half-life: ~6 days (acylated, subcutaneous)
CAS: 2381612-46-8
Product Specifications:
Purity: ≥98% (HPLC)
Form: Lyophilized Powder
Storage: −20 °C, protected from light
For research use only. Not for human consumption. Not for veterinary use. No medical or therapeutic claims are made. These statements have not been evaluated by the FDA.

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